Hyaluronic acid with or without bone marrow derived-mesenchymal stem cells improves osteoarthritic knee changes in rat model: a preliminary report.
نویسندگان
چکیده
Despite being a complex degenerative joint disease, studies on osteoarthritis (OA) suggest that its progression can be reduced by the use of hyaluronic acid (HA) or mesenchymal stem cells (MSC). The present study thus aims to examine the effects of MSC, HA and the combination of HA-MSC in treating OA in rat model. The histological observations using O'Driscoll score indicate that it is the use of HA and MSC independently and not their combination that delays the progression of OA. In conclusion, the preliminary study suggest that the use of either HA or MSCs effectively reduces OA progression better than their combined use.
منابع مشابه
Correction: Chondrocyte density, proteoglycan content and gene expressions from native cartilage are species specific and not dependent on cartilage thickness: a comparative analysis between rat, rabbit and goat
References 1. Kamisan N, Vasudevaraj Naveen S, Elina Ahmad R, Kamarul T: Chondrocyte density, proteoglycan content and gene expressions from native cartilage are species specific and not dependent on cartilage thickness: a comparative analysis between rat, rabbit and goat. BMC Veterinary Research 2013, 9:62. 2. Mahmod Suhaeb A, Naveen S, Mansor A, Kamarul T: Hyaluronic acid with or without bone...
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ورودعنوان ژورنال:
- Indian journal of experimental biology
دوره 50 6 شماره
صفحات -
تاریخ انتشار 2012